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English name: Prilocaine

English alias: 2-(propylamino)propion-o-toluidide;N - (2 - Methylphenyl) - 2 - (propylamino) propa - namide;Prilocaine base

CAS no. : 721-50-6

EINECS no. : 211-957-0

Molecular formula: C13H20N2O

Molecular weight: 220.31

Water solubility: soluble in water and ethanol, slightly soluble in chloroform

Physical and chemical properties:

Properties:

Needle crystal.37-38 ℃ melting point, boiling point of 159-162 ℃ (0.133 kPa), refractive index (nD20) 1.5299.Its hydrochloride ([1786-81-8]]) is a white crystalline powder.Melting point of 167-168 ℃.Soluble in water and ethanol, slightly soluble in chloroform.The taste is sour, bitter and odorless.

Preparation method:

After the condensation of o-toluidine and o-bromopropionyl bromide, the reaction with propylamine was performed to obtain propivacaine.

Product use:Local anesthetics.

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